Invitrogen™ Plasminogen Monoclonal Antibody (H16), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA543961

Product Code. 17654416

Description

Plasminogen is a plasma protein synthesized mostly in the liver. It consists of a single polypeptide chain and has a molecular weight of 88.5 kDa. The plasma concentration is usually in the range of 70 - 200 mg/L. Plasminogen is activated by tissue-plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Plasmin consists of a heavy (A-) chain which contains 5 kringles and a light (B-) chain with the active site. Plasmin is a trypsin-like protease whose natural substrate is fibrin, with binding sites for fibrin residing on the kringles. Plasmin is essential for fibrinolysis and decreased fibrinolytic potential due to congenital defects in plasmin can lead to recurring thrombosis, thrombophlebitis and pulmonary embolism.

Specifications

• Antigen: Plasminogen
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: P00747
• Gene Symbols: PLG
• Immunogen: Native protein, with N-terminal His Tag.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Clone: H16
• Conjugate: Unconjugated
• Gene: PLG
• Gene Alias: Ab1-346; Activation peptide; AI649309; angiostatin; DKFZp779M0222; Pg; plasmin; plasmin heavy chain A; Plasmin heavy chain A, short form; Plasmin light chain B; plasminogen; PLG; RP1-81D8.1
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 5340
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid