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Invitrogen™ PLAC1 Polyclonal Antibody

Product Code. 12829192
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12829192 100 μg 100µg
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Product Code. 12829192 Supplier Invitrogen™ Supplier No. PA521044

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human placenta lysate. PA5-21044 can be used with blocking peptide PEP-1158.

PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PLAC1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene PLAC1
Gene Accession No. Q9HBJ0
Gene Alias cancer/testis antigen 92; CT92; OOSP2L; PLAC1; placenta specific 1; placenta-specific 1; placenta-specific protein 1
Gene Symbols PLAC1
Host Species Rabbit
Immunogen A 15 amino acid peptide near the carboxy terminus of human PLAC1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10761
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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