Invitrogen™ PLA2G2A Polyclonal Antibody

Sheep Polyclonal Antibody

Brand:  Invitrogen™ PA547729

Product Code. 15538222

Description

In Western blots, approximately 60% cross-reactivity with recombinant mouse PLA2G2A is observed and less than 5% cross-reactivity with recombinant human (rh) PLA2G1B and rhPLA2G7 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.

Specifications

• Antigen: PLA2G2A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLA2G2A
• Gene Alias: EC 3.1.1.4; EF; Enhancing factor; eted enzyme type IIA phospholipase A2; GIIC sPLA2; Group IIA phospholipase A2; modifier of Min1; Mom1; non-pancreatic secreted type II phospholipase A2; non-pancreatic secretory phospholipase A2; NPS-PLA2; phosphatidylcholine 2-acylhydrolase 2A; phospholipase A2 group IIA; phospholipase A2, group IIA (platelets, synovial fluid); phospholipase A2, membrane associated; Pla2; PLA2B; PLA2BPLA2; PLA2G2A; PLA2L; PLA2LPLA2S; PLA2S; PLAS1; platelet phospholipase A2; RASF-A; secretory group II phospholipase A2; sPLA2; sPla2-IIA
• Host Species: Sheep
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5320
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P14555
• Gene Symbols: PLA2G2A
• Immunogen: Sf 21-derived recombinant human PLA2G2A Asn21-Cys144.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG