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Invitrogen™ PKP3 Polyclonal Antibody
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Product Code. 16351525
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Quantity:
100 μL
Unit Size:
100µL
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16351525 100 μL 100µL
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Product Code. 16351525 Supplier Invitrogen™ Supplier No. PA584574

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FDDIDLPSAV KYLMASDPNL QVLGAAYIQH KCYSDAAAKK QARSLQAVPR LVKLFNHANQ EVQRHATGAM RNLI Highest antigen sequence indentity to the following orthologs: Mouse - 99%, Rat - 99%.

Plakophilin-3 is an Armadillo-like protein present in nuclei and desmosomes of epithelial cells. The expression pattern of this protein seems to be largely restricted to epithelial cell types. Plakophilin-3 can be detected along cell borders in a punctuate staining pattern typical for desmosomal proteins. In addition to the desmosomal immunolocalization, immunostaining was observed as bright nuclear speckles. Thus, like plakophilin-1 and-2, plakophilin-3 displays a dual intracellular localization in the desmosomal plaque and in the cell nucleus, and therefore is probably involved in signal transduction pathways between the plasma membrane and the nucleus. The human protein has a predicted molecular mass of ~87 kDa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PKP3
Applications Immunohistochemistry (Paraffin), Immunocytochemistry, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PKP3
Gene Accession No. Q9Y446
Gene Alias 2310056L12Rik; Pkp3; plakophilin 3; plakophilin 3b; plakophilin-3
Gene Symbols PKP3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PKP3. Recombinant protein control fragment (Product #RP-104169).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11187
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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