Invitrogen™ PKD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5106237

Product Code. 16652675

Description

Antibody detects endogenous levels of total PKD2.

This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease.

Specifications

• Antigen: PKD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PKD2
• Gene Alias: A MGC138466; APKD2; Autosomal dominant polycystic kidney disease type II protein; C030034P18Rik; MGC138468; PC2; Pc-2; PKD2; PKD4; polycystic kidney disease 2; polycystic kidney disease 2 (autosomal dominant); polycystic kidney disease 2 homolog; Polycystic kidney disease 2 protein; Polycystic kidney disease 2 protein homolog; polycystin 2; polycystin 2, transient receptor potential cation channel; polycystin-2; Polycystwin; R48321; RGD1559992; transient receptor potential cation channel subfamily P member 2; transient receptor potential cation channel, subfamily P, member 2; TRPP1; TRPP2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5311
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q13563
• Gene Symbols: PKD2
• Immunogen: A synthesized peptide derived from human PKD2(Accession Q13563), corresponding to amino acid residues D788-E838.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG