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Description
Valosin containing protein (VCP), also designated TERA (for transitional endoplasmic reticulum ATPase), is a member of the AAA family of ATPases, which are involved in a variety of cellular activities. VCP is involved in a variety of membrane functions and in the regulation of the cell cycle. VCP associates with ubiquitinated IkB-a as well as with the 26S proteosome, indicating a potential role for VCP in the proteosome-mediated degradation of IkB-a. NVL (nuclear valosin-containing protein-like), also known as NVLp, is an 856 amino acid nuclear protein belonging to the AAA ATPase family. Implicated in ATP-dependent nuclear processes and ribosome synthesis, NVL exists as three alternatively spliced isoforms designated NVL isoform 1 (NVLp.2), NVL isoform 2 (NVLp.1) and NVL isoform 3. Widely expressed, NVL is found at highest levels in pancreas, retina, heart, skeletal muscle and placenta.
Specifications
Specifications
| Antigen | PINX1 |
| Applications | Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.33 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gene | PINX1 |
| Gene Accession No. | A4L691, Q96BK5, Q9CZX5 |
| Gene Alias | LPTL, LPTS, PIN2 interacting protein 1, Pin2 interacting protein X1, PINX1, Protein 67 11 3, TRF1 interacting protein 1 |
| Gene Symbols | PINX1 |
| Show More |
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