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Invitrogen™ PIM2 Recombinant Rabbit Monoclonal Antibody (K01_2N93)
Description
PIM2 Recombinant Monoclonal Antibody for Western Blot
PIM2 is a proto-oncogene which phosphorylates BAD, which partially inhibits its apopotopic function. PIM proteins (PIM-1, PIM-2 and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to Pim-1 with similar oncogenic functions. PIM-2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. PIM2 expression is negatively regulated by growth factor depletion. Increased levels of PIM-2 has also been observed in certain cancers.
Specifications
Specifications
| Antigen | PIM2 |
| Applications | Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K01_2N93 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 150mM NaCl, 0.05% BSA, 40% glycerol and 0.01% sodium azide; pH 7.4 |
| Gene | PIM2 |
| Gene Accession No. | Q9P1W9 |
| Gene Alias | DXCch3; PIM2; Pim-2; pim-2 oncogene; Pim-2 proto-oncogene, serine/threonine kinase; pim-2h; proto-oncogene Pim-2 (serine threonine kinase); proviral integration site 2; serine/threonine protein kinase pim-2; serine/threonine-protein kinase pim-2 |
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