Invitrogen™ PIM2 Recombinant Rabbit Monoclonal Antibody (JE55-57)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA542509

Product Code. 17769123

Description

Positive Control: Rat liver tissue lysate, mouse liver tissue lysate, human small intestine tissue lysate, 293T, A431, rat testis tissue, human liver tissue, human liver carcinoma tissue, human colon carcinoma tissue, mouse small intestine tissue, HepG2. Subcellular Location: Cytoplasm.

PIM2 is a proto-oncogene which phosphorylates BAD, which partially inhibits its apopotopic function. PIM proteins (PIM-1, PIM-2 and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to Pim-1 with similar oncogenic functions. PIM-2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. PIM2 expression is negatively regulated by growth factor depletion. Increased levels of PIM-2 has also been observed in certain cancers.

Specifications

• Antigen: PIM2
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q62070, Q9P1W9
• Gene Symbols: PIM2
• Immunogen: Synthetic peptide within C-terminal Human PIM2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: JE55-57
• Conjugate: Unconjugated
• Gene: PIM2
• Gene Alias: DXCch3; PIM2; Pim-2; pim-2 oncogene; Pim-2 proto-oncogene, serine/threonine kinase; pim-2h; proto-oncogene Pim-2 (serine threonine kinase); proviral integration site 2; serine/threonine protein kinase pim-2; serine/threonine-protein kinase pim-2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 11040, 18715, 317366
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid