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Invitrogen™ PIM2 Recombinant Rabbit Monoclonal Antibody (JE55-57)
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Product Code. 17769123
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Quantity:
100 μL
Unit Size:
100µL
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17769123 100 μL 100µL
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Product Code. 17769123 Supplier Invitrogen™ Supplier No. MA542509

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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: Rat liver tissue lysate, mouse liver tissue lysate, human small intestine tissue lysate, 293T, A431, rat testis tissue, human liver tissue, human liver carcinoma tissue, human colon carcinoma tissue, mouse small intestine tissue, HepG2. Subcellular Location: Cytoplasm.

PIM2 is a proto-oncogene which phosphorylates BAD, which partially inhibits its apopotopic function. PIM proteins (PIM-1, PIM-2 and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to Pim-1 with similar oncogenic functions. PIM-2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. PIM2 expression is negatively regulated by growth factor depletion. Increased levels of PIM-2 has also been observed in certain cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PIM2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JE55-57
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene PIM2
Gene Accession No. Q62070, Q9P1W9
Gene Alias DXCch3; PIM2; Pim-2; pim-2 oncogene; Pim-2 proto-oncogene, serine/threonine kinase; pim-2h; proto-oncogene Pim-2 (serine threonine kinase); proviral integration site 2; serine/threonine protein kinase pim-2; serine/threonine-protein kinase pim-2
Gene Symbols PIM2
Host Species Rabbit
Immunogen Synthetic peptide within C-terminal Human PIM2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11040, 18715, 317366
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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