Brusatol, MedChemExpress

Product Code. 16420268

Brand: Medchem Express HY19543

Description

MedChemExpress Brusatol (NSC 172924) is a unique inhibitor of the Nrf2 pathway that sensitizes a broad spectrum of cancer cells to Cisplatin and other chemotherapeutic agents. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Brusatol can be developed into an adjuvant chemotherapeutic agent. Brusatol increases cellular apoptosis.

Brusatol (NSC 172924) is a unique inhibitor of the Nrf2 pathway that sensitizes a broad spectrum of cancer cells to Cisplatin and other chemotherapeutic agents. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Brusatol can be developed into an adjuvant chemotherapeutic agent. Brusatol increases cellular apoptosis.

Specifications

• Chemical Name or Material: Brusatol
• CAS: 14907-98-3
• Color: White
• Purity Grade Notes: Research
• Molecular Formula: C₂₆H₃₂O₁₁
• Quantity: 5 mg
• Synonym: NSC 172924
• Solubility Information: DMSO : 25 mg/mL (48.03 mM; Need ultrasonic)
• SMILES: CC([C@](C[C@@](O1)2[H])3[H])=C(O)C(C[C@]3(C)[C@]4([H])[C@]2(CO[C@@]5([C@@H](O)[C@@H]4O)C(OC)=O)[C@@]5([H])[C@@H](OC(/C=C(C)/C)=O)C1=O)=O
• Molecular Weight (g/mol): 520.53
• Formula Weight: 520.53
• Percent Purity: 99.0%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-programmed cell death

Research purposes only