Invitrogen™ Human PIK3CA/PIK3R3 (p110 alpha/p55 gamma), His Tag Recombinant Protein

Product Code. 15980313

Brand: Invitrogen™ A31082

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This PIK3CA/PIK3R3 (p110 alpha /p55 gamma) recombinant human protein (full length) was expressed in insect cells. PIK3CA/PIK3R3 (p110 alpha /p55 gamma) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the Adapta™ assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Full Length, Recombinant, Active The gene accession number for PIK3CA is NP_006209.2 and for PIK3R3 is AAH21622.

PIK3CA/PIK3R3 lipid kinase (p110 alpha /p55 gamma) or Phosphatidylinositol 3-kinase (PIK3) phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position which serves as second messenger in growth signaling pathways. PIK3CA comprises a 110 kDa catalytic subunit and a regulatory subunit of either 85, 55, or 50 kDa. PIK3CA plays an important role in the metabolic actions of insulin, and a mutation in the PIK3CA has been associated with insulin resistance and plays an important role in glucose homeostasis in vivo. PIK3CA also plays an essential role in the development and induction of mast cells in normal and pathogenic immune responses.

Specifications

• Accession Number: P42336, Q92569
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM sodium phosphate with 150mM Imidazole, 0.25mM DTT, 25% glycerol, 0.1mM PMSF, 300mM NaCl and no preservative; pH 7
• Gene ID (Entrez): 5290, 8503
• Molecular Weight (g/mol): 125.4-56.3 kDa
• Name: Human PIK3CA/PIK3R3 (p110 alpha/p55 gamma), His Tag
• pH Range: 7
• Purification Method: Purified
• Quantity: 20 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: PIK3CA; PIK3R3
• Common Name: PIK3CA/PIK3R3
• Gene Symbol: PIK3CA, PIK3R3
• KinaseFamily: PI3 Kinase
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: Full length
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Shipping Condition: Dry Ice
• Expression System: Insect cells
• Protein Form: Full Length, Recombinant, Active
• Form: Liquid