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Invitrogen™ PIGY Polyclonal Antibody
Description
Despite its predicted molecular weight, PIG-Y often migrates at 28-30kDa in SDS-PAGE. A suggested positive control is human spleen tissue lysate. PA5-20652 can be used with blocking peptide PEP-0772.
Glycosylphosphatidylinositol (GPI) lipid anchoring is an important post-translational modification of proteins that takes place in the endoplasmic reticulum. The synthesis of GPI is initiated by GPI-N-acetylglucosaminyltransferase (GPI-GnT), a complex of proteins including PIG-A, PIG-H, PIG-C, GPI1, and DPM2. PIG-Y, the mammalian homolog to yeast Eri1p, is also thought to be involved in the biosynthesis of GPI. The PIG-Y gene encodes two proteins, one of which arises from leaky scanning of the mRNA.
Specifications
Specifications
| Antigen | PIGY |
| Applications | Immunohistochemistry, Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide |
| Gene | PIGY |
| Gene Accession No. | P0C1P0, Q3MUY2 |
| Gene Alias | 1810008A14Rik; HPMRS6; phosphatidylinositol glycan anchor biosynthesis class Y; phosphatidylinositol glycan anchor biosynthesis, class Y-like; phosphatidylinositol N-acetylglucosaminyltransferase subunit Y; Phosphatidylinositol-glycan biosynthesis class Y protein; Pigy; PIG-Y; Pigyl; PREY; protein preY |
| Gene Symbols | PIGY, Pigyl |
| Show More |
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