missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Crosslinking, Labeling and Protein Modification
  5. Protein Modification Reagents
  6. 10167633

Thermo Scientific™ Pierce™ SAT(PEG)4 (PEGylated N-succinimidyl S-acetylthioacetate)

Product Code. 10167633 Shop All Thermo Scientific Products
Change view
Click to view available options
Quantity:
100 mg
Unit Size:
100mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
10167633 100 mg 100mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 10167633 Supplier Thermo Scientific™ Supplier No. 26099

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Long (18.2A), pegylated form of SATA, an amine-reactive (NHS ester) sulfhydryl-addition reagent; contains 4-unit polyethylene glycol spacer arm.

Thermo Scientific™ Pierce SAT(PEG)4 is a long-arm (18.2 Ås), pegylated form of SATA, a sulfhydryl-addition reagent for covalent modification of primary amines to facilitate controlled, heterobifunctional crosslinking.

SAT(PEG)4 extends the flexibility, solubility and reach of other S-acetylthio (SAT) reagents for sulfhydryl modification of amine-containing molecules. SAT(PEG)4 has the same form as SATA and SATP, which are widely used as part of protein conjugation strategies. Two purified proteins (e.g., antibody and enzyme) are conjugated after modifying one protein with an SAT reagent and the other protein with a maleimide-activating crosslinker such as Sulfo-SMCC (Part No. 22322). Because SAT reagents add a protected sulfhydryl, the modified protein can be stored indefinitely before treating it to expose the sulfhydryl and performing the final sulfhydryl-directed conjugation reaction.The four-unit polyethylene glycol (PEG) group in SAT(PEG)4 provides increased hydrophilicity and spacer-arm length relative to SATA and SATP. When used in combination with a long-arm PEG-containing crosslinker like SM(PEG)12 (Part No. 22112), SAT(PEG)4 can be used to crosslink proteins with long spacers.

Highlights:

  • Reacts with primary amines to add protected sulfhydryls
  • An easy deprotection step generates a free sulfhydryl group
  • Water-soluble polyethylene glycol (PEG) spacer arm enhances solubility of labeled protein
TRUSTED_SUSTAINABILITY

Spécification

Chemical Reactivity Amine
Content And Storage Upon receipt store desiccated at -20°C. Product shipped at ambient temperature.
Label or Dye Sulfhydryl Group
Label Type Conjugating Groups
Product Line Pierce
Crosslinker Type Heterobifunctional
Reactive Moiety Active Ester, Succinimidyl Ester, NHS Ester
Spacer Long, PEGylated
Form Liquid
Quantity 100 mg
Solubility DMF, DMSO
Product Type Crosslinker
Afficher plus Afficher moins

For Research Use Only. Not for use in diagnostic procedures.

Nom du produit
Sélectionnez un problème

En cliquant sur Soumettre, vous reconnaissez que vous pouvez être contacté par Fisher Scientific au sujet des informations que vous avez fournies dans ce formulaire. Nous ne partagerons pas vos informations à d'autres fins. Toutes les informations de contact fournies seront également conservées conformément à notre politique de confidentialité. Politique de confidentialité.