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Piclamilast, Tocris Bioscience™

Potent and selective PDE4 inhibitor

Brand:  RD Systems (Bio-Techne) 4525/10

Code : Z1

Additional Details : Weight : 0.00010kg

Quantity 10mg

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Product Code. 13464884

  • £178.20 / 10mg


Estimated Shipment
03-09-2018
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Description

Description

Potent and selective inhibitor of phosphodiesterase (PDE) 4 (IC50 = 1 nM at PDE4 from human neutrophils). Displays >19,000-fold selectivity over other PDE isoenzymes. Exhibits anti-inflammatory effects in models of allergic inflammation. Also inhibits LTB4 synthesis in human neutrophils (IC50 = 2 nM).
Specifications

Chemical Identifiers

144035-83-6
381.253
3-(Cyclopentyloxy)-N-(3, 5-dichloro-4-pyridinyl)-4-methoxybenzamide
CHEBI:47619
C18H18Cl2N2O3
RRRUXBQSQLKHEL-UHFFFAOYSA-N
154575

Specifications

Piclamilast
144035-83-6
C18H18Cl2N2O3
RRRUXBQSQLKHEL-UHFFFAOYSA-N
3-cyclopentyloxy-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide
154575
381.25
10mg
>99%
3-(Cyclopentyloxy)-N-(3, 5-dichloro-4-pyridinyl)-4-methoxybenzamide
COC1=C(C=C(C=C1)C(=O)NC2=C(C=NC=C2Cl)Cl)OC3CCCC3
381.253
CHEBI:47619
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