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Piclamilast, Tocris Bioscience™

Catalog Number p-4817321
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
144035-83-6
C18H18Cl2N2O3
381.253
RRRUXBQSQLKHEL-UHFFFAOYSA-N
piclamilast, cpodpmb, 3-cyclopentyloxy-n-3,5-dichloropyridin-4-yl-4-methoxybenzamide, unii-wm58d7c3zt, 3-cyclopentyloxy-n-3,5-dichloro-4-pyridinyl-4-methoxybenzamide, wm58d7c3zt, benzamide, 3-cyclopentyloxy-n-3,5-dichloro-4-pyridinyl-4-methoxy, chembl42126, 3-cyclopentyloxy-n-3,5-dichloro-4-pyridyl-p-anisamide, 3-cyclopentyloxy-n-3,5-dichloro-4-pyridyl-4-methoxybenzamide
154575
CHEBI:47619
3-cyclopentyloxy-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide
COC1=C(C=C(C=C1)C(=O)NC2=C(C=NC=C2Cl)Cl)OC3CCCC3
This item is not returnable. View return policy
144035-83-6
C18H18Cl2N2O3
381.253
RRRUXBQSQLKHEL-UHFFFAOYSA-N
piclamilast, cpodpmb, 3-cyclopentyloxy-n-3,5-dichloropyridin-4-yl-4-methoxybenzamide, unii-wm58d7c3zt, 3-cyclopentyloxy-n-3,5-dichloro-4-pyridinyl-4-methoxybenzamide, wm58d7c3zt, benzamide, 3-cyclopentyloxy-n-3,5-dichloro-4-pyridinyl-4-methoxy, chembl42126, 3-cyclopentyloxy-n-3,5-dichloro-4-pyridyl-p-anisamide, 3-cyclopentyloxy-n-3,5-dichloro-4-pyridyl-4-methoxybenzamide
154575
CHEBI:47619
3-cyclopentyloxy-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide
COC1=C(C=C(C=C1)C(=O)NC2=C(C=NC=C2Cl)Cl)OC3CCCC3

Description

Potent and selective PDE4 inhibitor

Potent and selective inhibitor of phosphodiesterase (PDE) 4 (IC50 = 1 nM at PDE4 from human neutrophils). Displays >19,000-fold selectivity over other PDE isoenzymes. Exhibits anti-inflammatory effects in models of allergic inflammation. Also inhibits LTB4 synthesis in human neutrophils (IC50 = 2 nM).
Quantity 10 mg
Formula Weight 381.25
Percent Purity >99%
Chemical Name or Material Piclamilast
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