Invitrogen™ PIAS1 Recombinant Rabbit Monoclonal Antibody (JE36-84)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA544844

Product Code. 17837062

Description

PIAS1 Recombinant Monoclonal Antibody for Western Blot, IHC (P), Flow

PIAS1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in androgen receptor initiation and maintenance of spermatogenesis. The effects of transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.

Specifications

• Antigen: PIAS1
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O75925, O88907
• Gene Symbols: PIAS1
• Immunogen: Synthetic peptide within human PIAS1 aa 71-120/651.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: JE36-84
• Conjugate: Unconjugated
• Gene: PIAS1
• Gene Alias: 2900068C24Rik; AR interacting protein; Ddxbp1; DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1; DEAD/H box-binding protein 1; E3 SUMO-protein ligase PIAS1; E3 SUMO-protein transferase PIAS1; GBP; Gu binding protein; GU/RH-II; gu-binding protein; PIAS1; protein inhibitor of activated STAT 1; protein inhibitor of activated STAT protein 1; protein inhibitor of activated STAT, 1; protein inhibitor of activated STAT-1; RING-type E3 ubiquitin transferase PIAS1; RNA helicase II-binding protein; zinc finger, MIZ-type containing 3; ZMIZ3
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 56469, 8554
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid