Invitrogen™ PI3K p55 gamma Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5100897

Product Code. 16607384

Description

Antibody detects endogenous levels of total PIK3R3.

PIK3R3 binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. It is a component of a heterodimer of p110 (catalytic) and p55 (regulatory) subunits. The protein is expressed at highest levels in brain and testis. Lower levels are detected in adipose tissue, kidney, heart, lung and skeletal muscle. The protein contains 2 SH2 domains.

Especificaciones

• Antigen: PI3K p55 gamma
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pik3r3
• Gene Alias: AA414954; p55; p55-GAMMA; p55pik; phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55); phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; phosphatidylinositol 3-kinase p55 subunit; phosphatidylinositol 3-kinase regulatory subunit gamma; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma); phosphoinositide-3-kinase regulatory subunit 3; phosphoinositide-3-kinase, regulatory subunit 3 (gamma); PI3K regulatory subunit gamma; PI3-kinase p85 subunit gamma; PI3-kinase regulatory subunit gamma; PI3-kinase subunit p55-gamma; Pik3r3; ptdIns-3-kinase p85-gamma; ptdIns-3-kinase regulatory subunit gamma; ptdIns-3-kinase regulatory subunit p55-gamma; RP4-533D7.2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18710, 60664, 8503
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q63789, Q64143, Q92569
• Gene Symbols: Pik3r3
• Immunogen: A synthesized peptide derived from human PIK3R3, corresponding to a region within C-terminal amino acids.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG