Invitrogen™ PI3K p55 gamma Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5110170

Product Code. 17108103

Description

Immunogen sequence: PDLIQLRKIR DQHLVWLNHK GVRQKRLNVW LGIKNEDADE NYFINEEDEN LPHYDEKTWF VEDINRVQAE DLLYGKPDGA FLIRESSKK.

PIK3R3 binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. It is a component of a heterodimer of p110 (catalytic) and p55 (regulatory) subunits. The protein is expressed at highest levels in brain and testis. Lower levels are detected in adipose tissue, kidney, heart, lung and skeletal muscle. The protein contains 2 SH2 domains.

Specifications

• Antigen: PI3K p55 gamma
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pik3r3
• Gene Alias: AA414954; p55; p55-GAMMA; p55pik; phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55); phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; phosphatidylinositol 3-kinase p55 subunit; phosphatidylinositol 3-kinase regulatory subunit gamma; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma); phosphoinositide-3-kinase regulatory subunit 3; phosphoinositide-3-kinase, regulatory subunit 3 (gamma); PI3K regulatory subunit gamma; PI3-kinase p85 subunit gamma; PI3-kinase regulatory subunit gamma; PI3-kinase subunit p55-gamma; Pik3r3; ptdIns-3-kinase p85-gamma; ptdIns-3-kinase regulatory subunit gamma; ptdIns-3-kinase regulatory subunit p55-gamma; RP4-533D7.2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18710, 8503
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 2.2 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q64143, Q92569
• Gene Symbols: Pik3r3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-388 of human PIK3R3/p55PIK (NP_0036203).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG