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Eurofins DiscoverX PI3 Kinase (p110α/p85α) Human Protein

Product Code. 17300414
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Quantity:
20 μg
250 μg
Unit Size:
20µg
250µg
This item is not returnable. View return policy

Product Code. 17300414

Brand: Eurofins DiscoverX 14602

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This item is not returnable. View return policy

Description

Active complex of N-terminal His6-tagged recombinant full-length human p110α and untagged, recombinant, full length, human p85α, for use in Kinase Assays.

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.

GenBank U79143 / GenBank XM_043865

Specifications

Formulation mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol) 125.3 kDa (P110α) and 83.7 kDa (p85α)
Quantity 20 μg
Species Human
Recombinant Recombinant
Protein Tag N-terminal 6His / Untagged
Expression System Recombinant enzyme expressed in Sf21 insect cells
Protein Form Full-length
Purity or Quality Grade Combined ≥66%
Protein PI3 Kinase (p110α/p85α), active
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