missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Recombinant Proteins
  4. Eurofins DiscoverX PI3 Kinase (p110α (H1047R)/p85α) Mouse Protein

Eurofins DiscoverX PI3 Kinase (p110α (H1047R)/p85α) Mouse Protein

Product Code. 17390714
Encompass_Preferred
Click to view available options
Quantity:
10 μg
250 μg
Unit Size:
10µg
250µg
This item is not returnable. View return policy

Product Code. 17390714

Brand: Eurofins DiscoverX 14787M

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Complex of N-terminal 6His-tagged, recombinant, full-length mouse p110α containing the mutation H1047R α and untagged, recombinant, full length mouse p85α, for use in Kinase Assays.

The H1047R substitution in p110α is associated with a number of human cancers. The residue is conserved between the human and mouse sequences. In vitro studies have shown that this mutation confers increased lipid kinase activity compared to wild type, and is able to induce oncogenic transformation.

GenBank BC089038 / GenBank NM_001077495

Specifications

Formulation mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol) 129 kDa (p110α(H1047R)) and 83.6 kDa (p85α)
Quantity 250 μg
Species Murine
Recombinant Recombinant
Protein Tag N-terminal 6His / Untagged
Expression System Recombinant enzyme expressed in Sf21 insect cells
Protein Form Full-length
Purity or Quality Grade Combined ≥65%
Protein PI 3-Kinase (p110α(H1047R)/p85α), murine
Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.