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Eurofins DiscoverX PI3 Kinase (p110α (H1047R)/p85α) Mouse Protein
Beskrivelse
The H1047R substitution in p110α is associated with a number of human cancers. The residue is conserved between the human and mouse sequences. In vitro studies have shown that this mutation confers increased lipid kinase activity compared to wild type, and is able to induce oncogenic transformation.
GenBank BC089038 / GenBank NM_001077495
Tekniske data
Tekniske data
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
| Molecular Weight (g/mol) | 129 kDa (p110α(H1047R)) and 83.6 kDa (p85α) |
| Quantity | 250 μg |
| Species | Murine |
| Recombinant | Recombinant |
| Protein Tag | N-terminal 6His / Untagged |
| Expression System | Recombinant enzyme expressed in Sf21 insect cells |
| Protein Form | Full-length |
| Purity or Quality Grade | Combined ≥65% |
| Protein | PI 3-Kinase (p110α(H1047R)/p85α), murine |
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