Phospho-VASP (Ser238) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA538152

Product Code. 15515081

Description

VASP (vasodilator-stimulated phosphoprotein), is involved in the maintece of cytoarchitecture by interacting with actin-like filaments. VASP shares a limited degree of homology with the amino terminus of WASP, which is frequently mutated in WAS patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane. VASP is a protein of between 46 and 50 kDa that is highly expressed in human platelets and, like WASP, may play a role in cytoskeletal organization.

Specifications

• Antigen: Phospho-VASP (Ser238)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: VASP
• Gene Alias: VASP, Vasodilator-stimulated phosphoprotein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22323, 361517, 7408
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P50552, P70460
• Gene Symbols: VASP
• Immunogen: A synthetic phosphopeptide derived from human VASP around the phosphorylation site of Ser238 (K-V-SP-K-Q)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG