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Invitrogen™ Phospho-TIP60 (Ser90) Polyclonal Antibody
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Product Code. 15554721
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Quantity:
100 μL
Unit Size:
100µL
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15554721 100 μL 100µL
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Product Code. 15554721 Supplier Invitrogen™ Supplier No. PA537784

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Description

Rabbit Polyclonal Antibody

A suggested positive control for IHC is human brain tissue.

TIP60 is a transcription factor, originally isolated as an HIV-1 TAT-interactive protein, known to interact with the viral TAT protein that leads to HTATIP polyubiquitination and targets it for degradation. It belongs to the MYST family of histone acetyl transferases (HATs). TIP60 is a catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. A co-regulator of transcription factors, TIP60 either promotes or suppresses tumorigenesis. TIP60 is an enzyme that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-TIP60 (Ser90)
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene KAT5
Gene Accession No. Q8CHK4, Q92993, Q99MK2
Gene Alias 60 kDa Tat-interactive protein; AI839539; cPLA(2)-interacting protein; CPLA2; cPLA2 interacting protein; ESA1; histone acetyltransferase HTATIP; Histone acetyltransferase KAT5; HIV-1 Tat interactive protein; HIV-1 tat interactive protein 1, 60 kDa homolog; HIV-1 tat interactive protein 1, homolog; HIV-1 Tat interactive protein 60 kD; HIV-1 Tat interactive protein, 60 kD; HIV-1 Tat interactive protein, 60kDa; HIV-1 tat interactive protein, homolog; HTATIP; Htatip1; K(lysine) acetyltransferase 5; K-acetyltransferase 5; Kat5; Lysine acetyltransferase 5; PLIP; Tat interacting protein, 60kDa; Tat-interactive protein-60; TIP; Tip55; Tip60; TIP60(HTATIP); Tip60b; ZC2HC5
Gene Symbols KAT5
Host Species Rabbit
Immunogen Peptide sequence around phosphorylation site of Serine 90(P-G-S(p)-P-E) derived from Human Tip60.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10524, 192218, 81601
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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