Phospho-STAT6 (Y641) Mouse anti-Human, Mouse, APC, Clone: CHI2S4N, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-9013-42

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.20000kg



Disclaimers: For Research Use Only.

Product Code. 15215918

Quantity Price
1 £ 188.93 / 100 tests
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Antigen Phospho-STAT6 (Y641)
Concentration 5μL (0.06μg)/test
Gene Alias signal transducer and activator of transcription 6, pSTAT6
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Conjugate APC
Species Reactivity Human, Mouse
Isotype IgG2a
Applications Flow Cytometry (Intracellular Staining)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Host Species Mouse
Quantity 100 tests
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone CHI2S4N

This CHI2S4N monoclonal antibody recognizes human and mouse signal transducer and activator of transcription 6 (STAT6) when phosphorylated on tyrosine 641. Following their phosphorylation by JAKs, STAT proteins translocate to the nucleus where they bind to DNA and regulate transcription of specific genes in a cell type- and cytokine-specific manner. In response to IL-4, STAT6 is phosphorylated on tyrosine 641 by JAK1 and JAK3. STAT6 signaling downstream of the IL-4 receptor promotes T cell growth and B cell production of IgE.

Specificity of this CHI2S4N clone was determined by ELISA and flow cytometry.