Phospho-STAT6 (Y641) Mouse anti-Human, Mouse, APC, Clone: CHI2S4N, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 17-9013-42
UNSPSC : 12352200
Code : Z2
Additional Details : Weight : 0.20000kg
DescriptionThis CHI2S4N monoclonal antibody recognizes human and mouse signal transducer and activator of transcription 6 (STAT6) when phosphorylated on tyrosine 641. Following their phosphorylation by JAKs, STAT proteins translocate to the nucleus where they bind to DNA and regulate transcription of specific genes in a cell type- and cytokine-specific manner. In response to IL-4, STAT6 is phosphorylated on tyrosine 641 by JAK1 and JAK3. STAT6 signaling downstream of the IL-4 receptor promotes T cell growth and B cell production of IgE.
Specificity of this CHI2S4N clone was determined by ELISA and flow cytometry.
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
|Flow Cytometry (Intracellular Staining)|
|signal transducer and activator of transcription 6, pSTAT6|