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Phospho-STAT6 (Tyr641) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA517902
Code : LE
Additional Details : Weight : 0.01000kg
Description
It is not recommended to aliquot this antibody. This antibody is not cross-reactive with the corresponding phospho-tyrosine residues of other Stat proteins.
STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.Specifications
| Phospho-STAT6 (Tyr641) | |
| Polyclonal | |
| 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5 | |
| P42226 | |
| STAT6 | |
| Synthetic phosphopeptide corresponding to residues surrounding pTyr641 of human Stat6 | |
| 100 μL | |
| Primary | |
| Bovine, Human | |
| Antibody | |
| IgG |
| Immunocytochemistry, Immunoprecipitation, Western Blot | |
| Unconjugated | |
| STAT6 | |
| 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 353105, 6778 | |
| -20°C | |
| Liquid |