Invitrogen™ Phospho-STAM2 (Tyr371) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5105432

Product Code. 16671875

Description

Antibody detects endogenous levels of STAM2 only when phosphorylated at Tyr371.

The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.

Specifications

• Antigen: Phospho-STAM2 (Tyr371)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STAM2
• Gene Alias: 1200004O12Rik; 5730456G07Rik; BB145015; DKFZp564C047; Hbp; HGNC:11358; Hrs binding protein; hrs-binding protein; HSE1 homolog; signal transducing adapter molecule 2; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2; signal transducing adaptor molecule 2; STAM2; STAM-2; STAM2A; STAM2B; STAM-like protein containing SH3 and ITAM domains 2
• Host Species: Rabbit
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10254, 56324
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O75886, O88811
• Gene Symbols: STAM2
• Immunogen: A synthesized peptide derived from human STAM2(Accession O75886), corresponding to amino acid residues around phosphorylated Tyr371.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG