Invitrogen™ Phospho-SIN3A (Ser832) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5105063

Product Code. 16601515

Description

Antibody detects endogenous levels of SIN3A only when phosphorylated at Ser832.

Mammalian Sin3 (mSin3) is a 150 kDa protein closely related to the yeast SIN3 repressor protein involved in the transcriptional repression of many genes. There are two mammalian isoforms, mSin3A and mSin3B. Containing 4 paired amphipathic helix domains (PAH domains), mSin3A and mSin3B have been shown to directly interact with several other transcriptional repressor proteins including HDAC1, HDAC2, RbAp46, the methyl CpG binding protein MeCP2, the Mad/Max heterodimer, and the corepressors silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR).

Specifications

• Antigen: Phospho-SIN3A (Ser832)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIN3A
• Gene Alias: AW553200; Histone deacetylase complex subunit Sin3a; Kiaa4126; Mammalian Sin3A; mKIAA4126; mSin3A; Paired amphipathic helix protein Sin3a; SIN; Sin3; SIN3 homolog A, transcription regulator; SIN3 transcription regulator family member A; SIN3 transcription regulator homolog A; SIN3A; transcriptional corepressor Sin3a; transcriptional co-repressor Sin3A; transcriptional regulator, SIN3 yeast homolog A; transcriptional regulator, SIN3A; transcriptional regulator, SIN3A (yeast)
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20466, 25942, 363067
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q60520, Q96ST3
• Gene Symbols: SIN3A
• Immunogen: A synthesized peptide derived from human SIN3A(Accession Q96ST3), corresponding to amino acid residues around phosphorylated Ser832.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG