Invitrogen™ Phospho-SGK1 (Ser422) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ 441264G

Product Code. 10476653

Description

Phospho-SGK1 (Ser422) Polyclonal Antibody for Western Blot, IHC (P)

SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells. SGK plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.

Specifications

• Antigen: Phospho-SGK1 (Ser422)
• Classification: Polyclonal
• Formulation: Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
• Gene Accession No.: O00141
• Gene Symbols: SGK1
• Immunogen: The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human SGK1 that contains serine 422.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: SGK1
• Gene Alias: serine/threonine protein kinase SGK; serine/threonine-protein kinase Sgk1; serum and glucocorticoid-dependent protein kinase; serum/glucocorticoid regulated kinase 1; serum/glucocorticoid-regulated kinase 1; Sgk; SGK1; Sgk1 variant i3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6446
• Content And Storage: -20°C
• Form: Liquid