Invitrogen™ Phospho-RPS6KB2 (Ser423) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5105036

Product Code. 16631485

Description

Antibody detects endogenous levels of p70 S6 Kinase beta only when phosphorylated at Serine 423.

RPS6KB2 (p70S6K beta) is a serine/threonine kinase with 2 non-identical kinase catalytic domains which phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.

Specifications

• Antigen: Phospho-RPS6KB2 (Ser423)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rps6kb2
• Gene Alias: 70 kDa ribosomal protein S6 kinase 2; 70kDa; KLS; p70 ribosomal S6 kinase beta; p70 S6 kinase beta; p70 S6KB; p70 S6K-beta; p70(S6K)-beta; P70-beta; P70-beta-1; P70-beta-2; p70-S6K 2; P70S6K2; p70S6Kb; ribosomal protein S6 kinase B2; ribosomal protein S6 kinase beta-2; ribosomal protein S6 kinase, 70kD, polypeptide 2; ribosomal protein S6 kinase, 70kDa, polypeptide 2; ribosomal protein S6 kinase, polypeptide 2; RPS6KB2; S6 kinase 2; S6 kinase-related kinase; S6K2; S6K-beta; S6K-beta2; S6K-beta-2; serine/threonine-protein kinase 14 beta; serine/threonine-protein kinase 14B; SRK; STK14B
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 58988, 6199
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9UBS0, Q9Z1M4
• Gene Symbols: Rps6kb2
• Immunogen: A synthesized peptide derived from human RPS6KB2(Accession Q9UBS0), corresponding to amino acid residues around phosphorylated Ser423.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG