Invitrogen™ Phospho-RelB (Ser573) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA537726

Product Code. 15584661

Description

A suggested positive control for Western blot is HUVEC cells; suggested positive control for IHC is human breast carcinoma.

The NFkB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein. The DNAbinding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A second protein designated p52 (previously referred to as p49) has been identified that can act as an alternative NFkB subunit. Rel B does not bind with high affinity to NFkB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to that of p50 NFkB homodimers. However, Rel B/p50 heterodimers, in contrast to NFkB heterodimers, transactivates transcription of promotors containing kB binding sites.

Specifications

• Antigen: Phospho-RelB (Ser573)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RELB
• Gene Alias: avian reticuloendotheliosis viral (v-rel) oncogene related B; IREL; I-REL; OTTHUMP00000221313; rel b; RELB; REL-B; RELB proto-oncogene, NF-kB subunit; shep; transcription factor RelB; v-rel avian reticuloendotheliosis viral oncogene homolog B; v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3); v-rel reticuloen; v-rel reticuloendotheliosis viral oncogene homolog B; v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100360982, 19698, 5971
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q01201, Q04863
• Gene Symbols: RELB
• Immunogen: Peptide sequence around phosphorylation site of serine 573 (L-L-S(p)-P-G) derived from Human RelB.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG