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Phospho-RARA/RARB (Ser96) Polyclonal Antibody, Invitrogen™

Product Code. 16652375
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100 μL
Unit Size:
100µL
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16652375 100 μL 100µL
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Product Code. 16652375 Supplier Invitrogen Supplier No. PA5105934

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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Retinoic Acid Receptor alpha/beta only when phosphorylated at Retinoic AcSer96.

Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-RARA/RARB (Ser96)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RARB
Gene Accession No. P10276, P10826, P11416, P22605
Gene Alias A830025K23, HAP, HBV-activated protein, hepatitis B virus activated protein, MCOPS12, Nr1b1, Nr1b2, Nuclear receptor subfamily 1 group B member 1, nuclear receptor subfamily 1 group B member 2, nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long form, RAR, RAR alpha 1, RARA, RAR-alpha, RARalpha1, Rarb, RAR-beta, RARbeta1, RAR-epsilon, retinoic acid, retinoic acid nuclear receptor alpha variant 1, retinoic acid nuclear receptor alpha variant 2, retinoic acid receptor, retinoic acid receptor alpha, Retinoic acid receptor beta, retinoic acid receptor, alpha, retinoic acid receptor, alpha polypeptide, retinoic acid receptor, beta, retinoic acid receptor, beta polypeptide, RRB2
Gene Symbols RARA, RARB
Host Species Rabbit
Immunogen A synthesized peptide derived from human RARA(Accession P10276), corresponding to amino acid residues around phosphorylated Ser96.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19401, 218772, 24705, 24706, 5914, 5915
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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