Phospho-RARA/RARB (Ser96) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5105934

Product Code. 16652375

Description

Antibody detects endogenous levels of Retinoic Acid Receptor alpha/beta only when phosphorylated at Retinoic AcSer96.

Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma.

Specifications

• Antigen: Phospho-RARA/RARB (Ser96)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RARB
• Gene Alias: A830025K23, HAP, HBV-activated protein, hepatitis B virus activated protein, MCOPS12, Nr1b1, Nr1b2, Nuclear receptor subfamily 1 group B member 1, nuclear receptor subfamily 1 group B member 2, nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long form, RAR, RAR alpha 1, RARA, RAR-alpha, RARalpha1, Rarb, RAR-beta, RARbeta1, RAR-epsilon, retinoic acid, retinoic acid nuclear receptor alpha variant 1, retinoic acid nuclear receptor alpha variant 2, retinoic acid receptor, retinoic acid receptor alpha, Retinoic acid receptor beta, retinoic acid receptor, alpha, retinoic acid receptor, alpha polypeptide, retinoic acid receptor, beta, retinoic acid receptor, beta polypeptide, RRB2
• Host Species: Rabbit
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19401, 218772, 24705, 24706, 5914, 5915
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P10276, P10826, P11416, P22605
• Gene Symbols: RARA, RARB
• Immunogen: A synthesized peptide derived from human RARA(Accession P10276), corresponding to amino acid residues around phosphorylated Ser96.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG