Invitrogen™ Phospho-RAD17 (Ser656) Recombinant Superclonal™ Antibody (12HCLC)

Rabbit Recombinant Superclonal Antibody

Brand:  Invitrogen™ 711717

Product Code. 15993994

Description

This antibody is predicted to react with Monkey, Sheep and Bovine Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called 'Recombinant polyclonal antibody', this product is now rebranded as 'Recombinant Superclonal™ antibody'. The physical product and the performance remain unchanged.

Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.

Specifications

• Antigen: Phospho-RAD17 (Ser656)
• Classification: Recombinant Superclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Accession No.: O75943
• Gene Symbols: Rad17
• Immunogen: Peptide corresponding to Human RAD17 (aa 653-660).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Clone: 12HCLC
• Conjugate: Unconjugated
• Gene: Rad17
• Gene Alias: CCYC; cell cycle checkpoint protein (RAD17); cell cycle checkpoint protein RAD17; DNA damage checkpoint control protein RAD17; DNA repair exonuclease RAD17; FLJ41520; hRad17; MmRad24; R24L; RAD1 homolog; RAD17; RAD17 (Ser647); RAD17 checkpoint clamp loader component; RAD17 homolog; RAD17 homolog (S. pombe); Rad17 like protein; Rad17-like protein; Rad17p; RAD17SP; RAD24; RF-C activator 1 homolog; RF-C/activator 1 homolog; YOR368W
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5884
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid