Invitrogen™ Phospho-PKC zeta (Thr410) Recombinant Rabbit Monoclonal Antibody (HL1278)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA546895

Product Code. 17830906

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. PKC zeta plays a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function.

Specifications

• Antigen: Phospho-PKC zeta (Thr410)
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P09217, Q02956, Q05513
• Gene Symbols: PRKCZ
• Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Thr410 of human PKC zeta. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: HL1278
• Conjugate: Unconjugated
• Gene: PRKCZ
• Gene Alias: 14 - 3 - 3 - zeta isoform; 14-3-3-zetaisoform; AI098070; aPKCzeta; atypical protein kinase C; C80388; kinase nPKC-zeta; KPCZ; nPKC-zeta; nPKC-zeta PRKCZ; PKC2; Pkcz; PKC-ZETA; Prkcz; protein kinase C zeta; protein kinase C zeta subspecies; protein kinase C zeta type; protein kinase C, zeta; r14-3-3; R74924; zetaPKC
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 18762, 25522, 5590
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid