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Invitrogen™ Phospho-PKC epsilon (Ser729) Polyclonal Antibody
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Product Code. 10690464
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For Research Use Only. All usage must comply with product instructions.
 
Product Code. 10690464 Supplier Invitrogen™ Supplier No. 44977G

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This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 

Description

Rabbit Polyclonal Antibody

Phospho-PKC epsilon (Ser729) Polyclonal Antibody for Western Blot

The PKC family of serine/threonine kinases, including PRKCE (PKC epsilon), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. Protein kinase C (PKC) can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-PKC epsilon (Ser729)
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
Gene PRKCE
Gene Accession No. P16054, Q02156
Gene Alias 5830406C15Rik; MGC125656; MGC125657; nPKC-epsilon; PKC e; PKC[e]; Pkce; Pkcea; PKCepsilon; PRKCE; PRKCH; protein kinase C; protein kinase C epsilon; protein kinase C epsilon type; protein kinase C, epsilon; protein kinase C, eta; R75156
Gene Symbols PRKCE
Host Species Rabbit
Immunogen The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human PKCe that contains serine 729. The sequence is conserved in mouse and rat.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18754, 5581
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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