Invitrogen™ Phospho-PIK3C2B (Tyr228) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA572388

Product Code. 15951055

Description

Phospho-PIK3C2B (Tyr228) Polyclonal Antibody for Western Blot

The Class II PI3 kinases, including PIK3C2B, phosphorylate the 3 position of PI or PI4P. Though not as well studied as the class I PI3 kinases, the class II enyzmes have been linked to diverse, receptor-mediated cellular processes including insulin signaling, neuronal survival, and growth factor signaling. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Specifications

• Antigen: Phospho-PIK3C2B (Tyr228)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PIK3C2B
• Gene Alias: C2-PI3K; C330011J12Rik; Gm199; phosphatidylinositol 3-kinase C2 domain-containing beta polypeptide; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta; phosphoinositide 3-kinase-C2-beta; phosphoinositide-3-kinase, class 2, beta polypeptide; pi3kc2b; PI3KC2beta; PI3K-C2beta; PI3K-C2-beta; PIK3C2B; PTDINS-3-kinase C2 beta; ptdIns-3-kinase C2 subunit beta
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5287
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: O00750
• Gene Symbols: PIK3C2B
• Immunogen: KLH conjugated synthetic peptide between 215-250 amino acids from human.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG