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Phospho-Phospholamban (Ser16, Thr17) Polyclonal Antibody, Invitrogen™
Description
PLB is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases; whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.
Specifications
Specifications
| Antigen | Phospho-Phospholamban (Ser16, Thr17) |
| Applications | Immunocytochemistry, Immunofluorescence, Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | PLN |
| Gene Accession No. | P26678, P61014, P61016 |
| Gene Alias | PLN; phospholamban; CMD1P; PLB; cardiac phospholamban; CMH18 |
| Gene Symbols | PLN |
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