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Phospho-PDCD4 (Ser457) Polyclonal Antibody, Invitrogen™

Product Code. 15525721
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Quantity:
100 μg
Unit Size:
100µg
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15525721 100 μg 100µg
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Product Code. 15525721 Supplier Invitrogen Supplier No. PA538806

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Description

Rabbit Polyclonal Antibody

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-PDCD4 (Ser457)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PDCD4
Gene Accession No. Q53EL6, Q61823, Q9JID1
Gene Alias neoplastic transformation inhibitor
Gene Symbols PDCD4
Host Species Rabbit
Immunogen A synthetic phosphopeptide derived from human PDCD4 around the phosphorylation site of Ser457 (F-V-SP-E-G)
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18569, 27250, 64031
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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