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Invitrogen™ Phospho-p130Cas (Tyr410) Polyclonal Antibody
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Product Code. 15564711
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Quantity:
100 μL
Unit Size:
100µL
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15564711 100 μL 100µL
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Product Code. 15564711 Supplier Invitrogen™ Supplier No. PA537775

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Description

Rabbit Polyclonal Antibody

A suggested positive control for Western blot is K562 or NIH-3T3 cells; suggested positive control for IHC is human breast carcinoma.

The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-p130Cas (Tyr410)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene BCAR1
Gene Accession No. P56945
Gene Alias AI385681; BCA1; Bcar1; BCAR1 scaffold protein, Cas family member; BCAR1, Cas family scaffold protein; BCAR1, Cas family scaffolding protein; breast cancer anti-estrogen resistance 1; breast cancer anti-estrogen resistance protein 1; Cas; Cas scaffolding protein family member 1; CAS1; CASS1; CRKAS; CRK-associated substrate; Crk-associated substrate p130Cas; OTTHUMP00000174941; p130 Cas; P130CAS; p130Cas (pTyr410); p130Cas (pY410); p130Cas phospho; phospho p130Cas; v-crk-associated tyrosine kinase substrate
Gene Symbols BCAR1
Host Species Rabbit
Immunogen Peptide sequence around phosphorylation site of tyrosine 410(G-V-Y(p)-A-V) derived from Human p130 Cas.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9564
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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