Phospho-OCT1 (POU2F1) (Ser385) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5105826

Product Code. 16664535

Description

Antibody detects endogenous levels of POU2F1/OCT1 only when phosphorylated at Ser385.

OCT1 (POU2F1) is a ubiquitously expressed transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. It modulates transcription transactivation by NR3C1, AR and PGR. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.

Specifications

• Antigen: Phospho-OCT1 (POU2F1) (Ser385)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POU2F1
• Gene Alias: 2810482H01Rik; NF-A1; OCT1; oct-1; oct-1B; octamer binding protein 1; octamer-binding protein 1; Octamer-binding transcription factor 1; Octamer-binding transcription factor-1; Otf1; OTF-1; POU class 2 homeobox 1; POU domain, class 2, transcription factor 1; Pou2f1; ubiquitous transcription factor
• Host Species: Rabbit
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171068, 18986, 5451
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P14859, P25425, P31503
• Gene Symbols: POU2F1
• Immunogen: A synthesized peptide derived from human POU2F1(Accession P14859), corresponding to amino acid residues around phosphorylated Ser385.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG