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Invitrogen™ Phospho-NFkB p100 (Ser870) Polyclonal Antibody
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Product Code. 15564601
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Quantity:
100 μL
Unit Size:
100µL
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15564601 100 μL 100µL
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Product Code. 15564601 Supplier Invitrogen™ Supplier No. PA537663

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Description

Rabbit Polyclonal Antibody

A suggested positive control for Western blot is MDA-MB-435 cells; suggested positive control for IHC is human breast carcinoma; suggested positive control for ICC/IF is Hela cells.

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-NFkB p100 (Ser870)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Nfkb2
Gene Accession No. Q00653, Q9WTK5
Gene Alias CVID10; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; lyt; Lyt10; LYT-10; NF kappaB2; NF-kappaB2; NF-kB p100; NFKB, p52/p100 subunit; NFKB2; NF-kB2; nuclear factor kappa B subunit 2; nuclear factor Kappa-B, subunit 2; nuclear factor NF-kappa-B p100 subunit; Nuclear factor NF-kappa-B p52 subunit; nuclear factor of Kappa light chain gene enhancer in B cells 2; nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100); nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100; oncogene Lyt-10; p100; p49; p49/p100; p50B; p52; RGD1307189; transcription factor NFKB2
Gene Symbols Nfkb2
Host Species Rabbit
Immunogen Peptide sequence around phosphorylation site of serine 870(Y-G-S(p)-Q-S) derived from Human NF-kappa-B-p100/p52.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18034, 309452, 4791
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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