Invitrogen™ Phospho-NFATC1 (Ser172) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA564696

Product Code. 15702766

Description

Phospho-NFATC1 (Ser172) Polyclonal Antibody detects endogenous levels of NFATC1 only when phosphorylated at Ser172.

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Specifications

• Antigen: Phospho-NFATC1 (Ser172)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NFATC1
• Gene Alias: 2210017P03Rik; AI449492; AV076380; MGC138448; NFAT tra; NFAT trans; NFAT transcription complex cytosolic component; NFAT2; NFATc; NF-ATC; NFATC1; NF-ATc1; NF-ATc1.2; Nfatcb; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1; nuclear factor of activated T-cells 1; nuclear factor of activated T-cells 'c'; nuclear factor of activated T-cells, cytoplasmic 1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1; transcription factor NF-ATc
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18018, 4772
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol, 0.5% BSA and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O88942, O95644
• Gene Symbols: NFATC1
• Immunogen: A synthesized peptide derived from human NFAT2 (Phospho-Ser172).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG