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Invitrogen™ Phospho-MYOD (Thr115) Polyclonal Antibody
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Product Code. 16671945
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Quantity:
100 μL
Unit Size:
100µL
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16671945 100 μL 100µL
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Product Code. 16671945 Supplier Invitrogen™ Supplier No. PA5105502

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of MyoD1 only when phosphorylated at Thr115.

The Myogenic determination gene (MyoD) was first identified by the virtue of its ability to convert embryonic mouse fibroblast cells to muscle cells. It was subsequently shown that forced expression of MyoD (human homolog is myf 3) gene in a wide variety of normal and neoplastic cells could either convert the cells to muscle cells or activate a set of the otherwise transcriptionally inactive muscle-specific genes in these cells. The regulatory domain of the MyoD gene product lies within a 70 amino acid region and comprises a basic DNA binding motif and a helix-loop-helix (HLH) dimerization motif. Subsequent studies identified three other genes whose products shared sequence homology for the basic HLH domain of MyoD. These are; myf5, myogenin (human homolog is myf4) and myf6 (also known as MRF4 and herculin).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-MYOD (Thr115)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MYOD1
Gene Accession No. P10085, P15172, Q02346
Gene Alias AI503393; bHLHc1; Class C basic helix-loop-helix protein 1; CMD1; MYF3; Myf-3; Myoblast determination protein 1; myoblast determination protein 1 homolog; Myod; MYOD1; Myod-1; MYOD1 homolog; myogenic differentiation 1; myogenic factor 1; myogenic factor 3; PUM; unnamed protein product
Gene Symbols MYOD1
Host Species Rabbit
Immunogen A synthesized peptide derived from human MYOD1(Accession P15172), corresponding to amino acid residues around phosphorylated Thr115.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17927, 337868, 4654
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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