Phospho-MyD88 (Tyr257) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA564835

Product Code. 15772896

Description

Phospho-MyD88 (Tyr257) Polyclonal Antibody detects endogenous levels of MyD88 only when phosphorylated at Tyr257.

Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS. MyD88 recruits IRAK to IL-1 receptor complex in response to IL-1. This pathway further leads to activation of NF-kB. MyD88 has a wide tissue distribution.

Specifications

• Antigen: Phospho-MyD88 (Tyr257)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYD88
• Gene Alias: mutant myeloid differentiation primary response 88; Myd88; MYD88D; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88; myeloid differentiation primary response protein MyD88
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17874, 301059, 4615
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P22366, Q6Y1S1, Q99836
• Gene Symbols: MYD88
• Immunogen: A synthesized peptide derived from human Myd88 (Phospho-Tyr257)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG