Invitrogen™ Phospho-MPZL1 (Tyr260) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5105440

Product Code. 16651885

Description

Antibody detects endogenous levels of PZR only when phosphorylated at Ser260.

Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

Specifications

• Antigen: Phospho-MPZL1 (Tyr260)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mpzl1
• Gene Alias: 1110007A10Rik; FLJ21047; immunoglobulin family transmembrane protein; Mpzl1; MPZL1b; myelin protein zero like 1; myelin protein zero-like 1; myelin protein zero-like protein 1; protein zero related; protein zero-related; Pzr; PZR1b; PZRa; PZRb; UNQ849/PRO1787
• Host Species: Rabbit
• Purification Method: Sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 68481, 9019
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O95297, Q3TEW6
• Gene Symbols: Mpzl1
• Immunogen: A synthesized peptide derived from human MPZL1(Accession O95297), corresponding to amino acid residues around phosphorylated Ser260.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG