Invitrogen™ Phospho-MKK7 (Ser271, Thr275) Recombinant Rabbit Monoclonal Antibody (MKK7S271T275-R4F9), FITC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA537007

Product Code. 17136598

Description

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined.

Specifications

• Antigen: Phospho-MKK7 (Ser271, Thr275)
• Classification: Recombinant Monoclonal
• Conjugate: FITC
• Gene: MAP2K7
• Gene Alias: 2; 5930412N11Rik; c-Jun N-terminal kinase kinase 2; Dual specificity mitogen-activated protein kinase kinase 7; EMBL:AAX61178.1}; JN; JNK kinase 2; JNK-activating kinase 2; JNKK; JNKK 2; Jnkk2; MAP kinase kinase 7; MAP2K4; map2k7; map2k7 {ECO:0000312; MAPK/ERK kinase 4; MAPK/ERK kinase 7; MAPKK 4; MAPKK 7; MAPKK7; MEK; MEK 4; MEK 7; Mek7; mitogen activated protein kinase kinase 7; mitogen-activated protein kinase kinase 7; Mkk7; PRKMK7; protein kinase, mitogen activated, kinase 7; SAPK kinase 1; SAPK kinase 4; SAPK/ERK kinase 1; SAPKK1; SAPKK-1; SAPKK4; SAPKK-4; SEK1; sek2; SKK4; Stress-activated protein kinase kinase 4
• Host Species: Rabbit
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 5609
• Content And Storage: 4°C, store in dark
• Form: Liquid

• Applications: Flow Cytometry
• Clone: MKK7S271T275-R4F9
• Formulation: PBS with 0.20% BSA and 0.09% sodium azide
• Gene Accession No.: O14733
• Gene Symbols: MAP2K7
• Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser271 and Thr275 of human MKK7.
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG κ