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Invitrogen™ Phospho-mGluR7 (Ser862) Polyclonal Antibody
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Product Code. 15398154
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Quantity:
100 μL
Unit Size:
100µL
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15398154 100 μL 100µL
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Product Code. 15398154 Supplier Invitrogen™ Supplier No. PA535397

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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, canine, non-human primate and zebrafish based on 100% sequence homology. This antibody contains enough material to conduct 10 mini-Western blots.

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
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Specifications

Antigen Phospho-mGluR7 (Ser862)
Applications Western Blot
Classification Polyclonal
Concentration ∼0.25 mg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 0.1 mg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene GRM7
Gene Accession No. P35400, Q68ED2
Gene Alias 6330570A01Rik; BB176677; C030018L03; E130018M02Rik; FLJ40498; G protein-coupled receptor GRM7; G protein-coupled receptor, family C, group 1, member G; GLUR7; glutamate metabotropic receptor 7; glutamate receptor; glutamate receptor, metabotropic 7; Gpr1g; Gprc1g; GRM7; Metabotropic glutamate receptor 7; metabotropic glutamate receptor mGluR7; metabotropic glutamate receptor subtype 7b; MGLU7; mGlu7a receptor; MGLUR7; PPP1R87; protein phosphatase 1, regulatory subunit 87
Gene Symbols GRM7
Host Species Rabbit
Immunogen Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser862 of rat GRM7 conjugated to KLH.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 108073, 81672
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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