Invitrogen™ Phospho-MARCKS (Ser27) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5105557

Product Code. 16622005

Description

Antibody detects endogenous levels of MARCKS only when phosphorylated at Ser27.

MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

Specifications

• Antigen: Phospho-MARCKS (Ser27)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MARCKS
• Gene Alias: 80K protein; 80K-L; 80K-L protein; FLJ14368; FLJ90045; KINC; Macs; MARCKS; MARCS; myristoylated alanine rich protein kinase C substrate; myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; PKCSL; PRKCSL; protein kinase C substrate 80 kDa protein; protein kinase C substrate, 80 kDa protein, light chain
• Host Species: Rabbit
• Purification Method: Sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17118, 25603, 4082
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P26645, P29966, P30009
• Gene Symbols: MARCKS
• Immunogen: A synthesized peptide derived from human MARCKS(Accession P29966), corresponding to amino acid residues around phosphorylated Ser27.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG