Phospho-Kir3.1 (Ser185) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA538572

Product Code. 15565491

Description

This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

Specifications

• Antigen: Phospho-Kir3.1 (Ser185)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNJ3
• Gene Alias: KCNJ3, GIRK1, Kcnf3, KIR3.1, GIRK-1, HGIRK1, KGA
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16519, 3760, 50599
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P48549, P63250, P63251
• Gene Symbols: KCNJ3
• Immunogen: A synthetic phosphopeptide derived from human GIRK1/KIR31/KCNJ3 around the phosphorylation site of Ser185 (K-M-SP-Q-P)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG