Invitrogen™ Phospho-HNRNPA0 (Ser84) Polyclonal Antibody

Product Code.	Quantity	unitSize
16622535	100 μL	100µL

Product Code. 16622535 Supplier Invitrogen™ Supplier No. PA5106091

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of HNRNPA0 only when phosphorylated at Ser84.

HNRPA0 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus. This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus.

Specifications

• Antigen: Phospho-HNRNPA0 (Ser84)
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: Hnrnpa0
• Gene Accession No.: Q13151, Q9CX86
• Gene Alias: 1110055B05Rik; 3010025E17Rik; Heterogeneous nuclear ribonucleoprotein A0; hnRNA binding protein; hnRNP A0; HNRNPA0; Hnrpa0
• Gene Symbols: Hnrnpa0
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human HNRNPA0(Accession Q13151), corresponding to amino acid residues around phosphorylated Ser84.
• Purification Method: Sequential chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10949, 498696, 77134
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG