Phospho-Histone H1.3 (Thr18) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5101017

Product Code. 16614255

Description

Antibody detects endogenous levels of Histone H1.3 only when phosphorylated at Thr18.

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq].

Specifications

• Antigen: Phospho-Histone H1.3 (Thr18)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H1-3
• Gene Alias: H1 histone family, member 3, H1 VAR.4, H1.3, H1D, H1f3, H1s-2, H1s-4, Hist1h1d, histone 1, family 3, histone 1, H1d, histone cluster 1, H1d, histone H1.3, Histone H1c, histone H1s-2
• Host Species: Rabbit
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14957, 3007
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P16402, P43277
• Gene Symbols: H1-3, HIST1H1D
• Immunogen: A synthesized peptide derived from human HIST1H1E(Accession P10412), corresponding to amino acid residues around phosphorylated Thr18.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG