Invitrogen™ Phospho-HIST1H2BC (Ser14) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5144326

Product Code. 17918642

Description

Phospho-HIST1H2BC (Ser14) Polyclonal Antibody for Western Blot, ELISA

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The protein has antibacterial and antifungal antimicrobial activity. The main transcript variant of this gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. This transcript variant lacks a polyA tail but instead contains a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: Phospho-HIST1H2BC (Ser14)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H2BC5
• Gene Alias: dJ221C16.3; H2B Clustered Histone 4; H2B histone family, member L; H2B.1; H2B/a; H2B/g; H2B/h; H2B/k; H2B/l; H2BC10; H2BC4; H2BC6; H2BC7; H2BC8; H2BFA; H2BFG; H2BFH; H2BFK; H2BFL; HIST1H2BC; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI; histone 1, H2bc; histone cluster 1, H2bc; histone H2B type 1-C/E/F/G/I; Histone H2B.1 A; Histone H2B.a; Histone H2B.g; Histone H2B.h; Histone H2B.k; Histone H2B.l
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3017
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
• Gene Accession No.: P58876, P62807
• Gene Symbols: H2BC5, Hist1h2bc
• Immunogen: Peptide sequence around site of Phospho-Ser (14) derived from Human Histone H2B type 1-C/E/F/G/I.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG