Invitrogen™ Phospho-HDAC6 (Ser22) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5105035

Product Code. 16621485

Description

Antibody detects endogenous levels of HDAC6 only when phosphorylated at Serine 22.

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.

Specifications

• Antigen: Phospho-HDAC6 (Ser22)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HDAC6
• Gene Alias: CPBHM; FLJ16239; Hd6; HDA6; Hdac5; Hdac6; histone deacetylase 5; histone deacetylase 6; Histone deacetylase mHDA2; JM21; KIAA0901; mHDA2; PPP1R90; protein phosphatase 1, regulatory subunit 90; scurfy candidate 6; Sfc6
• Host Species: Rabbit
• Purification Method: Sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10013, 15185
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9UBN7, Q9Z2V5
• Gene Symbols: HDAC6
• Immunogen: A synthesized peptide derived from human HDAC6(Accession Q9UBN7), corresponding to amino acid residues around phosphorylated Ser22.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG